A systematic review and meta-analysis of Hymenolepis nana in human and rodent hosts in Iran: A remaining public health concern

Hymenolepis nana, as a neglected zoonotic helminth, naturally occurs in both humans and rodents. Herein, systematic review meta-analysis was carried out to estimate pooled prevalence of H. nana infection among human rodent hosts for the first time Iran. PubMed, Web Science, Scopus, Embase databases (English articles) SID Magiran (Persian were systematically searched relevant studies published from inception till May 24, 2020. Chi2 I2 index used assess heterogeneity included studies. Publication bias assessed using Egger's intercept visual inspection funnel plot. Pooled estimated random-effects model with 95 % confidence interval (CI) depicted forest STATA software analysis. The overall 1.2 (95 CI = 1.0–1.4%). Subgroup analysis revealed 2.2 1.8–2.6%) 0.5 0.3 0.8 %) school children food handlers, respectively. In terms hosts, 13 9.3–16.6%). highest rate Rattus spp. (19.6 %; 10.6–28.6%), genus synanthropic behavior. It seems, despite advancement sanitation infrastructure hygiene status, compares other helminthic diseases remains challenging public health problem